Sunday, June 24, 2012

You Are Not You--Part 2


All this anti-bacterial frenzy ignores the truth that our bodies cannot live without our friends the bacteria. In just the last few decades has science begun to realize the beneficial role of many types of internal bacteria. We’d best learn to call a truce in our bacterial wars, or we’re gonna crash and become part of our own “collateral damage.”

But breeding new species of super bugs is not the only unfortunate fallout of our war on bacteria. Some recent research seems to be pointing the way toward the increasing incidence of autoimmune diseases and other chronic modern ailments. It’s still a mystery exactly why such diseases as Crohn’s disease, type 1 diabetes, multiple sclerosis, and others are escalating, but our blundering is probably involved. We are altering our environment and upsetting biological balances that were built over eons. It’s becoming clear that antibiotics are a significant cause of autoimmune disorders. How?

The driving force behind our immune system is not a self-contained mechanism run by us, but is created primarily by beneficial bacteria. Ever since we became a separate species (about 200,000 years ago), our immune system has been able to tread a delicate balance between being too lax (thus failing to detect and battle foreign pathogens) and too aggressive (and attacking our own cells). Beneficial bacteria have trained our immune system to achieve that crucial balance. It’s not our own DNA that does the job, but bacterial (non-human) DNA. But now we’re upsetting that balance. We’ve saturated our bodies with antibiotics to the point that our immune system is confused and sometimes attacks our own cells.

Another way we mess up our immune system is by not exposing babies to dirt. We’ve become so obsessed with protecting our newborns from nasty bugs that we raise them in as sterile an environment as we can. Meeting a paucity of microorganisms, their immune systems never get a chance to become robust and balanced. This is a particular problem today, as more women are receiving cesarean sections to deliver their babies. The womb is an incredible bug-shielding organ. As an embryo develops from two cells to a trillion, it can safely do so in the womb’s sterile environment—without being turned into some kind of monster by mom’s invading bugs. But to survive in this dirty world, a newborn must very quickly develop its immune system. That process begins as it descends the bacterial-laden birth canal, and continues, as the baby sucks bacterial-laden mother’s milk and inhales Uncle Charlie’s bacterial-laden breath.

But a baby born by C-section immediately pops from a sterile womb into a germ infested world, with no preparation in the birth canal. We aggravate the situation by spraying disinfectant on everything that baby touches. Result: an out-of-balance immune system that goes haywire and either allows otherwise harmless bacteria to beat it down or goes into overdrive and attacks itself.

So the next time your doctor starts to write you out a prescription for a course of antibiotics for some non-lethal infection, you might think about declining. The next time you talk with an expectant mother, you might caution her about the sterile danger of a C-section and encourage her to breastfeed. If neither of these opportunities arises, express a little gratitude for all the friendly foreign critters who make their abode inside you. Your life literally depends on them!

[Note: Some of the information that stimulated this posting is found in the
June 2012 issue of Scientific American.]

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